Coronavirus pandemic (COVID-19), McMahon D.E., Amerson E., Rosenbach M., et al. Pityriasis rosea and ringworm look similar. Women are 50% more likely to develop pityriasis rosea. In a registry-based study, PR-like eruption was observed in only 12% of patients (14). (b) Patient 1: Closeup of a plaque. Dermatol Res Pract. Dermatol Ther. (d) Patient 2: Closeup of plaques, with the hyperpigmented centre and trailing scale. PR also tends to occur in patients between the ages of 10 to 35 that are usually otherwise healthy, Lam says. SARS-CoV-2 spike protein positivity in pityriasis rosea-like and urticaria-like rashes of COVID-19. Careers. Human herpesvirus-6, -7, and Epstein-Barr virus reactivation in pityriasis rosea during COVID-19. Disclaimer. While unusual, one patient developed pityriasis rosea once a year for five years in a row. While annoyingly itchy, the rash does not cause any serious long-term side effects and is not contagious, unlike the diseases these vaccines protect against. Epub 2021 Aug 7. Unfortunately, due to her deteriorating neurologic status, her associated symptoms were not evaluated properly. -, Broccolo F., Drago F., Careddu A.M., et al. doi: 10.1111/ajd.13504. 8600 Rockville Pike Cutis. -, Cyrenne BM, Al-Mohammedi F, DeKoven JG, Alhusayen R. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 vaccine. -, Recalcati S. Cutaneous manifestations in COVID-19: a first perspective. J Eur Acad Dermatol Venereol. MeSH Please enable it to take advantage of the complete set of features! government site. Some studies have identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike proteins on endothelial cells and lymphocytes from PR-like lesions, consistent with direct viral invasion (3, 4). Vaccine-induced pityriasis rosea and pityriasis rosea-like eruptions: a review of the literature. These findings were consistent with a diagnosis of PR-like eruption. doi: 10.1111/bjd.20143. Pityriasis rosea-like eruptions following vaccination with BNT162b2 mRNA COVID-19 Vaccine J Eur Acad Dermatol Venereol. However, after 14 days, she developed multiple discrete blanching erythematous oval patches and plaques on the lower abdomen, back, and bilateral upper thighs (Figures 1A,B). Some treatments can alleviate related symptoms, including itching. -. J Med Virol 2021; 93: 18501851. 9500 Euclid Avenue, Cleveland, Ohio 44195 |, Important Updates + Notice of Vendor Data Event. Pityriasis rosea following CoronaVac COVID-19 vaccination: a case report. 2021;35(8):e489e491. Pityriasis Rosea | Johns Hopkins Medicine It looked like one, and it certainly itched like one but then more came. Medicine (Baltimore). It has been reported that pityriasis rosea has been triggered by several vaccines, as a rare side-effect. -. The etiopathogenesis of PR is still unknown, but is frequently associated with episodes of upper respiratory tract infections. Unable to load your collection due to an error, Unable to load your delegates due to an error. The https:// ensures that you are connecting to the The https:// ensures that you are connecting to the Would you like email updates of new search results? 2022 Jul 21;14(7):e27108. doi: 10.12998/wjcc.v5.i6.203, 6. The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. However, if you scratch your patches, you may break your skin, leading to an infection that can cause pain. Epub 2022 Jan 5. | Pityriasis Rosea, COVID-19 and . Pityriasis means scaly, and rosea means pink, but the rashes may look red, gray, brown or purple. Epub 2022 Jun 13. Nevertheless, the incidence of skin reactions after mRNA vaccinations was low. Central dusky-red erythematous on some plaques (A); almost all lesions fading with associated post-inflammatory hyperpigmentation after treatment (B). The patches may itch. Br J Dermatol 2021. If you have pityriasis rosea, its unlikely that youll get it again. J Am Acad Dermatol. Among the common cutaneous manifestations of COVID-19 (e.g., morbilliform eruptions, chilblains, and varicella-like vesicles), PR and PR-like eruptions have rarely been described (6, 7). To the best of our knowledge, there have been no reports of PR-like eruptions following inoculation with Oxford/AstraZeneca ChAdOx1 nCoV-19 (AZD1222) vaccine. Dermatol Ther. Common causes of drug-induced PR-like eruptions include angiotensin-converting enzyme inhibitors, non-steroidal anti-inflammatory drugs, and gold. doi: 10.1111/ijd.13061. Human herpesvirus6, 7, and EpsteinBarr virus reactivation in pityriasis rosea during COVID19. J Invest Dermatol. doi: 10.1007/s10103-019-02783-8, 16. Some research shows that people who follow a Mediterranean diet have lower levels of inflammation in their bodies. Unauthorized use of these marks is strictly prohibited. "It looks very different.". Pityriasis rosea is a benign inflammatory rash that starts with a single red rash, also known as the "herald patch," which eventually gives way to a larger, similar-looking rash on the trunk. Despite this rare complication, our report highlights that the presence of PR-like eruption is not a contraindication for subsequent vaccinations. These types cannot cause cold sores or genital herpes. However, adverse effects to COVID-19 vaccines, particularly cutaneous reactions, have been reported. Clinical findings of pityriasis rosealike eruption in the patients. However, several adverse effects of COVID-19 vaccination have been identified. sharing sensitive information, make sure youre on a federal sharing sensitive information, make sure youre on a federal (2019) 34:185764. doi: 10.1111/dth.13650, 7. Published by Wolters Kluwer Health, Inc. Coronavirus: Five skin conditions linked to COVID-19 after - 9News She diagnosed it as pityriasis rosea, a benign but frustratingly itchy rash that in her words just happens sometimes. Even though it is benign, it can cause substantial. 2021 Sep 7;8:752443. doi: 10.3389/fmed.2021.752443. Pityriasis Lichenoides - Dermatologic Disorders - Merck Manuals This site needs JavaScript to work properly. Front. However, there isnt enough research to determine that stress may cause pityriasis rosea. 2022 Nov 1;43(6):555-558. doi: 10.2500/aap.2022.43.220058. Pityriasis rosea-like eruption revealing COVID-19. Coming to a Cleveland Clinic location?Hillcrest Cancer Center check-in changesCole Eye entrance closingVisitation, mask requirements and COVID-19 information, Notice of Intelligent Business Solutions data eventLearn more. Pityriasis rosea following SARS-CoV-2 vaccination: A case series. . Federal government websites often end in .gov or .mil. Some treatments can alleviate related symptoms, including itching. Herald patch of pityriasis rosea. Vote for your favorite beauty products now! doi: 10.1111/jdv.17301. eCollection 2021. Cutaneous Complications of mRNA and AZD1222 COVID-19 Vaccines: A Worldwide Review. Int J Infect Dis. The condition is more prevalent in spring and fall. Pityriasis rosea, COVID-19 and vaccination: new keys to understand an old acquaintance. PR is a common self-limited papulosquamous eruption typically presenting with a large solitary pink-colored patch or plaque (i.e., herald patch), followed by secondary eruptions of smaller erythematous patches or plaques with associated peripheral collarette scaling distributed along the cleavage lines of the trunk, forming a Christmas tree pattern (5). [Epub ahead of print]. Pityriasis rosea Gibert type rash in an asymptomatic patient that tested positive for COVID-19. eCollection 2022 Jul. doi: 10.1016/j.jaad.2020.04.094, 8. Pityriasis Rosea Induced by COVID preview & related info | Mendeley (c) Patient 2: Thin red to tan oval plaques with peripheral scale on the trunk and proximal thigh. (2017) 9:7399. doi: 10.4081/dr.2017.7399, 17. Cutaneous Complications of mRNA and AZD1222 COVID-19 Vaccines: A Worldwide Review. Though there's no single-known cause, it may be brought on by a drug interaction, or the reactivation of herpes simplex virus 6 or 7. Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine. Variable dermatological manifestations including acral erythema, urticaria, vasculitis, vesicular or pustular eruptions, maculopapular rash have all been reported during the course of COVID19. Cutis. Pityriasis Rosea. Human herpesvirus-6,7, and Epstein-Barr virus reactivation in pityriasis rosea during COVID-19. Pityriasis rosea-like Covid-arm Erythema multiforme Erythroderma Psoriasis Others Grover-like eruptions Herpes simplex reactivation: 24 1 17 4 2 2 1 1 20 15 9 5 2 1 1 1 3 3: 21.5 0.9 15 3.5 1.8 1.8 0.9 0.9 Pityriasis rosea is a benign inflammatory rash that starts with a single red rash, also known as the "herald patch," which eventually gives way to a larger, similar-looking rash on the trunk. Also, topical medication with dermatocorticosteroids and emollients was associated. Careers. Its important to pay attention to your skin. Dtsch Arztebl Int. Bookshelf Please enable it to take advantage of the complete set of features! government site. Epub 2021 May 10. Rare Heterogeneous Adverse Events Associated with mRNA-Based COVID-19 Vaccines: A Systematic Review. Pityriasis Lichenoides. -, Polack FP, Thomas SJ, Kitchin N et al. 2022 Jan;114:88-89. doi: 10.1016/j.ijid.2021.10.055. sharing sensitive information, make sure youre on a federal Before Pityriasis Rosea Shortly After mRNA-1273 COVID-19 Vaccination. 8 Types of Rashes That Can Be a Sign of COVID-19 - Health Among patients who received inactivated vaccines, another case of PR-like eruption was reported four days after the first dose of CoronaVac (SinoVac) (1). Some people who have had cosmetic fillers used to remove . HHS Vulnerability Disclosure, Help Please enable it to take advantage of the complete set of features! What at-home treatments do you recommend? Pityriasis rosea (PR)-like eruption is a rare cutaneous complication of immunization. Epub 2021 Apr 26. Keywords: sharing sensitive information, make sure youre on a federal Pityriasis rosea is a benign inflammatory rash that starts with a single red rash, also known as the "herald patch," which eventually gives way to a larger, similar-looking rash on the trunk within days or weeks, says dermatologist Corey L. Hartman, founder of Skin Wellness Dermatology in Birmingham, Alabama. MeSH Cutis. Pityriasis rosea: Who gets and causes - American Academy of Dermatology Curr Dermatol Rep. 2022;11(4):289-312. doi: 10.1007/s13671-022-00370-9. Drug-induced PR-like eruption accounts for 2% of all cutaneous adverse drug reactions (10). It may appear on any part of your body, but it usually appears on the trunk (torso), arms and legs. Pityriasis rosea developing after COVID19 vaccination Zendaya Shows Off Her Short Sunshine Curls. Br J Dermatol. Martora F, Battista T, Marasca C, Genco L, Fabbrocini G, Potestio L. Clin Cosmet Investig Dermatol. 2022 May;121(5):1003-1007. doi: 10.1016/j.jfma.2021.12.028. (https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4291919/). Copyright 2021 Leerunyakul, Pakornphadungsit and Suchonwanit. Epub 2022 Feb 9. Cureus. Pityriasis rosea-like eruption presenting as multiple discrete erythematous oval patches and plaques on the back (A) lower abdomen, and bilateral upper thighs (B); lesions distributed along cleavage lines without prominent scales (C). Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. 2022 Mar 15;10(3):624. doi: 10.3390/microorganisms10030624. FOIA (2020) 33:e13878. In my experience, patients with darker skin are more likely to present with atypical forms of the disorder. While home remedies are safe for most people, its a good idea to check with your healthcare provider before trying some of the following options. Department of Dermatology, Graduate School of Medicine, Kyusyu University, Japan. As vaccine reactogenicity reports continue to surface, dermatologists and other health care providers should understand the landscape of the latest cutaneous reactions to guide and address patients' concerns. To the best of our knowledge, there have been no reports of PR-like eruptions following inoculation with Oxford/AstraZeneca ChAdOx1 nCoV-19 (AZD1222) vaccine. and transmitted securely. Bethesda, MD 20894, Web Policies Your rash looks infected (red, purple, gray or white skin; irritation and swelling). Pityriasis rosea Gibert is an erythematous-papulosquamous dermatosis that frequently occurs in young adults. We present two cases of COVID-19 vaccine-induced pityriasis rosea. Use of this site constitutes acceptance of our eCollection 2022 Feb. Kroumpouzos G, Paroikaki ME, Yumeen S, Bhargava S, Mylonakis E. Microorganisms. (2015) 2015:253154. doi: 10.1155/2015/253154, 14. Laboratory investigation results (i.e., complete blood count, blood chemistry, C-reactive protein level, erythrocyte sedimentation rate, serological test for syphilis, plasma polymerase chain reaction (PCR) for human herpesvirus (HHV)-6 and HHV-7, and reverse transcription-PCR for COVID-19) were unremarkable. Most people with the rash are 10 to 35 years of age. National Library of Medicine Pityriasis rosea as a cutaneous manifestation of COVID19 infection Although the exact pathophysiologic mechanisms of PR after vaccination remain unclear, immune responses to COVID-19 vaccines and disruption of T-cell mediated control of latent infections were implicated (12, 1518). Any product that may be evaluated in this article, or claim that may be made by its manufacturer, is not guaranteed or endorsed by the publisher. JAAD Int. 2022 Nov;36(11):1947-1968. doi: 10.1111/jdv.18294. Pityriasis rosea (pih-tuh-RY-uh-sis ROH-zee-uh) is a common skin condition that causes patches of your skin to develop raised, scaly rashes. 2022 Jun;7:164-168. doi: 10.1016/j.jdin.2022.01.009. KL and KP collated resources. 2022 Mar 15;10(3):624. doi: 10.3390/microorganisms10030624. doi: 10.1097/MD.0000000000029823. This article presents a case of PR in a 66-year-old black male 1 week after administration of the Pfizer-BioNTech COVID-19 vaccine. Due to the temporal relationship between vaccination and onset of rash, COVID-19 vaccination was the most likely etiology. In approximately 50% of people with pityriasis rosea, the patches itch. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). The patient had a positive RT-PCR result, and was confirmed with SARS-CoV-2 infection. government site. Safety and efficacy of the BNT162b2 mRNA Covid-19 vaccine. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). The .gov means its official. Pityriasis rosea-like eruptions following vaccination with BNT162b2 The .gov means its official. COVID-19 has been reported as one such viral trigger for PR. 2022 Jul 8;101(27):e29823. 2021 Sep;60(9):1150-1151.doi: 10.1111/ijd.15700. A spectrum of cutaneous reactions to SARs-CoV-2 (COVID-19) vaccines have been reported in the literature. doi: 10.1111/jdv.17342, 5. Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Pityriasis rosea after mRNA COVID-19 vaccination Int J Dermatol. A virus may cause pityriasis rosea, but experts aren't sure. Pityriasis rosea after administration of Pfizer-BioNTech COVID-19 vaccine Pityriasis Rosea Induced by COVID-19 Vaccination Eur J Case Rep Intern Med. World J Clin Cases. official website and that any information you provide is encrypted 1 Several vaccines have been developed to fight against COVID19, to prevent the transmission among susceptible individuals and to decrease the morbidity 2022 Aug 11;9(8):43. doi: 10.3390/medicines9080043. 2022 Nov;36(11):1947-1968. doi: 10.1111/jdv.18294. This rash is thought to be caused by a virus. It is likely that a new viral trigger of pityriasis rosea is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Lasers Med Sci. Physical examination revealed that lesions were distributed along cleavage lines, similar to PR, without herald patch or prominent scales (Figure 1C). Pityriasis Rosea Following Pfizer-BioNTech Vaccination in an Adolescent Girl. 2021 Dec;108(6):317-318. doi: 10.12788/cutis.0411. Disclaimer. Careers. 8600 Rockville Pike doi: 10.1111/jdv.17342. 2020 Jul;33(4):e13730. The site is secure. Federal government websites often end in .gov or .mil. Dermatol Ther. Suchonwanit P, Leerunyakul K, Kositkuljorn C. Cutaneous manifestations in COVID-19: Lessons learned from current evidence. (2021). PMC Fortunately, PR-like eruption is responsive to topical corticosteroids without any systemic adverse effects. The authors have no conflicts of interests to disclose. Previously, PR has been reported in temporal association with various viral inoculations. Is there a prescription cream or ointment that you can prescribe? The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Treatment was initiated with systemic corticosteroid therapy - hydrocortisone hemisuccinate 200 mg/day for 7 days, and loratadine 10 mg 2 times a day. Disclaimer. 78 PDF Pityriasis rosea following CoronaVac COVID19 vaccination: a case report Elin Akda, N. Ilter, B. t, . Erdem Unable to load your collection due to an error, Unable to load your delegates due to an error. Clipboard, Search History, and several other advanced features are temporarily unavailable. Ehsani AH, Nasimi M, Bigdelo Z. Pityriasis rosea as a cutaneous manifestation of COVID-19 infection. These patches are smaller than the herald patch they range from 1 to 2 cm and are often called daughter patches. and transmitted securely. Atypical pityriasis rosea associated with mRNA COVID-19 vaccine. The patients/participants provided their written informed consent to participate in this study. Involvement of the oral mucosa has also been reported in as many as 50% of all cases (11). Your California Privacy Rights. Numerous scattered erythematous, Pityriasis rosea. Get many smaller patches or bumps on your skin. Yes, There Is a Correct Order for Everything You Do in the Shower, Each Zodiac Sign's Unique Personality Traits, Swoopy 1960s Hair Was Everywhere at the SAG Awards, Christina Aguilera Opened Up About Getting Injections and Why She Doesn't Care If People Judge Her, "I think we all can rely on a little help. The symptoms of pityriasis rosea usually develop in stages: Pityriasis rosea doesnt hurt. Bethesda, MD 20894, Web Policies Some people develop a few large patches on their skin. PMC In addition to COVID-19 vaccination, she was currently taking medications (i.e., levetiracetam and thyroxin) for glioblastoma, and the two drugs had been prescribed for approximately nine months. This patch is the herald or mother patch. Polack FP, Thomas SJ, Kitchin N, et al. 8600 Rockville Pike Before While you don't need to treat the rash, some patients ask for treatment to take care of the following. These conditions lasted 8.6 days on average. HHS Vulnerability Disclosure, Help Figure 1. 2022 Dec;9:127. doi: 10.1016/j.jdin.2022.03.018. (2021) 60:11501. COVID-19; HHV, human herpes virus; Moderna; PR; PR, pityriasis rosea; PR-LE; PR-LE, pityriasis rosea-like eruption; Pfizer; coronavirus; dermatology; mRNA vaccine; mRNA, messenger RNA; pityriasis rosea; pityriasis rosealike eruption; vaccine. Women and young people are most likely to have these reactions. Histopathological Patterns of Cutaneous Adverse Reaction to Anti-SARS-CoV-2 Vaccines: The Integrative Role of Skin Biopsy. Before Table 1. (Unfortunately, I scratched my rash until it bled, so my hyperpigmentation may linger.). Bin Rubaian NF, Almuhaidib SR, Aljarri SA, Alamri AS. JAAD Case Rep. 2021;7:9394. Unauthorized use of these marks is strictly prohibited. At first, I thought it was a mosquito bite. I video-chatted with my dermatologist who asked a few questions: Did I have body aches or flu-like symptoms? Hardin J. Pityriasis Rosea. The clinical and pathologic spectrum of mucocutaneous reactions FOIA Washrawirul C, Triwatcharikorn J, Phannajit J, Ullman M, Susantitaphong P, Rerknimitr P. J Eur Acad Dermatol Venereol. New York City-based dermatologist Macrene Alexiades. -, Busto-Leis J.M., Servera-Negre G., Mayor-Ibarguren A., et al. Br J Dermatol. As King notes, there have been some reported cases of pityriasis rosea occurring in patients after receiving certain vaccines, like the flu shot. eCollection 2022. Epub 2022 Feb 9. Diagnoses: Epub 2020 Jun 29. It has been reported that pityriasis rosea has been triggered by several vaccines, as a rare side-effect. 2022 Oct;123:58-69. doi: 10.1016/j.ijid.2022.06.037. Atypical pityriasis rosea associated with mRNA COVID19 vaccine E. Bostan, Adam Jarbou Published 29 September 2021 Medicine Journal of Medical Virology Variable dermatological manifestations including acral erythema, urticaria, vasculitis, vesicular or pustular eruptions, maculopapular rash have all been reported during the course of Covid-19. Pityriasis Rosea Associated With COVID-19 Vaccination: A Common Rash Following Administration of a Novel Vaccine. ", The 29 Best Valentines Day Gifts for the Men in Your Life. J Eur Acad Dermatol Venereol 2020;34:e4367. Medicines (Basel). I also had to stop working out and hiking for about a week, as Alexiades is right excessive perspiration worsened the itch. The authors have no conflicts of interest to declare. (2021) 85:4655. But some patients also are developing delayed skin reactions on. Unauthorized use of these marks is strictly prohibited. -, Carballido Vzquez A.M., Morgado B. Pityriasis rosea-like eruption after Pfizer-BioNTech COVID-19 vaccination. Pityriasis rosea is a common condition that causes discolored patches on your skin. Pityriasis rosea is a common condition that causes discolored patches on your skin. National Library of Medicine Cutaneous reactions after COVID-19 vaccination in Turkey: A multicenter study. J Eur Acad Dermatol Venereol. Dermatol Reports. N Engl J Med 2020; 383: 2603-2615. The typical distribution of the rash is on the trunk between the neck and the knees.". Pityriasis rosea (PR)-like eruption is a rare cutaneous complication of immunization. The material on this site may not be reproduced, distributed, transmitted, cached or otherwise used, except with the prior written permission of Cond Nast. Case Report: Pityriasis Rosea-Like Eruption Following COVID-19 Vaccination. 2022 May;11(2):222-225. doi: 10.7774/cevr.2022.11.2.222. Epub 2022 May 31. Australas J Dermatol. In some cases, central hyperpigmentation was identified. Few brownish patches also appeared, suggestive of post-inflammatory hyperpigmentation. Coronavirus: Five skin conditions linked to COVID-19 - Sky News 2022 Nov 6;15:2369-2382. doi: 10.2147/CCID.S388245. Viruses, Variants, and Vaccines: How COVID-19 Has Changed the Way We Look at Skin. Epub 2021 May 29. Pityriasis rosea-like rash after messenger RNA COVID-19 vaccination: A case report and review of the literature. National Library of Medicine The https:// ensures that you are connecting to the See this image and copyright information in PMC. doi: 10.1016/j.jaad.2021.03.092, 15. FOIA eCollection 2022. Lawley LP, McCall CO, Lawley TJ. How can you tell that I have pityriasis rosea? Due to the rising incidence of coronavirus disease 2019 (COVID-19) worldwide, mass vaccination has been the cornerstone in preventing viral spread and decreasing morbidity and mortality. Generalized Papulovesicular Eruption as a Side Effect of the Pfizer-BioNTech COVID-19 Vaccine. This site needs JavaScript to work properly. Chanprapaph K, Pomsoong C, Tankunakorn J, Eden C, Suchonwanit P, Rutnin S. Comparative analyses of clinical features, histopathology, and CD123 immunohistochemistry of oral lupus erythematosus, lichen planus, and other lichenoid lesions. "And it has a particular [dermatomal] distribution because it's along a nerve," which also presents as fluid-filled blisters, rather than lesions. Epub 2022 Jun 21. A more recent letter in the International Journal of Dermatology reported a "unique case of pityriasis rosea following administration of mRNA COVID-19 vaccine." Your symptoms dont improve after treatment. In conclusion, we have described the first case of PR-like eruption following ChAdOx1 nCoV-19 (Oxford/AstraZeneca) vaccination. Advertising on our site helps support our mission. Accessibility 2022 Feb 3;9 (2):003164. doi: 10.12890/2022_003164. F. Drago, G. Ciccarese, A. Parodi Int J Dermatol. Inverse pityriasis rosea secondary to COVID-19 vaccination. Suchonwanit P, Leerunyakul K, Kositkuljorn C. Diagnostic and prognostic values of cutaneous manifestations in COVID-19. Frontiers | Case Report: Pityriasis Rosea-Like Eruption Following COVID PR is a rare cutaneous reaction after mRNA vaccination against SARS-CoV-2. (a) Patient 1: Thin red to tan oval plaques with peripheral scale on the trunk. . Vaccinations have been identified to rarely cause several cutaneous reactions. Treatment with topical 0.1% triamcinolone acetonide twice per day showed partial response after seven days. Though pityriasis rosea is a common skin rash, it can still make you feel self-conscious, and it can be unpleasant if it itches. Disclaimer. The average time between vaccination and rash onset is 10 days, and most patients experience pruritus (70%). An official website of the United States government. Cazzato G, Ambrogio F, Pisani MC, Colagrande A, Arezzo F, Cascardi E, Dellino M, Macorano E, Trilli I, Parente P, Lettini T, Romita P, Marzullo A, Ingravallo G, Foti C. Vaccines (Basel).